Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 6/20 | 0.51 |
| ▸ | THRB | P10828 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7228631 | 1.00 | THRA (0.51) | THRATHRBMEN1KMT2AESR1 | |
| SCHEMBL7229660 | 0.94 | RARB (0.57) | THRATHRBMEN1KMT2AESR1 | |
| SCHEMBL7229653 | 0.94 | RARB (0.57) | THRATHRBMEN1KMT2AESR1 | |
| SCHEMBL7232399 | 0.94 | THRA (0.51) | THRATHRBMEN1KMT2AESR1 | |
| SCHEMBL7232408 | 0.94 | THRA (0.51) | THRATHRBMEN1KMT2AESR1 | |
| SCHEMBL7229153 | 0.87 | THRA (0.46) | THRATHRBMEN1KMT2AESR1 | |
| SCHEMBL7229149 | 0.87 | THRA (0.46) | THRATHRBMEN1KMT2AESR1 | |
| SCHEMBL7232362 | 0.87 | THRA (0.49) | THRATHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL7232356 | 0.87 | THRA (0.49) | THRATHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL7239557 | 0.87 | HRH3 (0.48) | THRATHRBMEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6623810-B2 | Refractive index anisotropy | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-09-23 | — | — | US | disclosed |
| US-20010050353-A1 | Phenylacetylene compound, liquid crystal composition, and liquid crystal element produced with the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-12-13 | — | — | US | disclosed |
| EP-0781827-B1 | Liquid crystal mixture and liquid crystal device comprising the same | SUMITOMO CHEMICAL CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| US-6149837-A | SUBSTITUTED 1,4-BIS(SUBSTITUED PHENYLACETYLENE)BENZENE WHERE AT LEAST ONE RING HAS AN ALKYL ATTACHMENT, HAS A LARGE ANISOTROPY OF REFRACTIVE INDEX, TENDS TO BE MIXED WITH OTHER LIQUID CRYSTALS, IS LIGHT STABLE; LIQUID CRYSTAL ELEMENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0781827-A1 | Liquid crystal mixture and liquid crystal device comprising the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-02 | — | — | EP | disclosed |