Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 11/20 | 0.39 |
| ▸ | PPARA | Q07869 | 11/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6722406 | 0.92 | EPHX2 (0.45) | EPHX2CYP2C9CYP2C19CYP2J2PPARG | |
| SCHEMBL6718358 | 0.86 | EPHX2 (0.42) | EPHX2CYP2C9CYP2C19CYP2J2PPARG | |
| SCHEMBL6712965 | 0.84 | EPHX2 (0.41) | EPHX2CYP2C9CYP2C19CYP2J2PPARG | |
| SCHEMBL6713371 | 0.76 | EPHX2 (0.45) | EPHX2CYP2C9CYP2C19CYP2J2PPARG | |
| SCHEMBL6716079 | 0.72 | EPHX2 (0.41) | EPHX2CYP2C9CYP2C19CYP2J2PPARA | |
| SCHEMBL6715079 | 0.72 | GCG (0.48) | PPARGPPARAPPARDTRPV1 | |
| SCHEMBL6713208 | 0.71 | GCG (0.48) | PPARGPPARAPPARDALDH1A1RAB9A | |
| SCHEMBL6715966 | 0.70 | GCG (0.49) | PPARGPPARAPPARDTRPV1NPC1 | |
| SCHEMBL6713102 | 0.70 | GCG (0.49) | PPARGPPARAPPARDNPC1RAB9A | |
| SCHEMBL28012489 | 0.70 | L3MBTL1 (0.51) | EPHX2CYP2C9CYP2C19CYP2J2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528525-B1 | Amidocarboxylic acid derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-03-04 | — | — | US | claimed |