Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.42 |
| ▸ | FDPS | P14324 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27670042 | 1.00 | TP53 (0.50) | TP53GPR84FDPSFFAR1LMNA | |
| SCHEMBL27670048 | 1.00 | TP53 (0.50) | TP53GPR84FDPSFFAR1LMNA | |
| SCHEMBL27649785 | 1.00 | TP53 (0.50) | TP53GPR84FDPSFFAR1LMNA | |
| SCHEMBL11761626 | 1.00 | TP53 (0.50) | TP53GPR84FDPSFFAR1LMNA | |
| SCHEMBL11756733 | 1.00 | TP53 (0.50) | TP53GPR84FDPSFFAR1LMNA | |
| SCHEMBL11223496 | 0.98 | TP53 (0.48) | TP53GPR84FDPSFFAR1LMNA | |
| SCHEMBL7228863 | 0.98 | TP53 (0.52) | TP53GPR84FDPSFFAR1LMNA | |
| SCHEMBL8521185 | 0.91 | TP53 (0.43) | TP53FDPSCA2CA1 | |
| SCHEMBL1111713 | 0.81 | — | — | |
| SCHEMBL6363952 | 0.80 | CA2 (0.42) | TP53GPR84FDPSFFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602876-B1 | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2003-08-05 | — | — | US | disclosed |
| US-6204280-B1 | OXAZOLIDINONE DERIVATIVE, ANTICOAGULANT | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKTER HAFTUNG (DE) | 2001-03-20 | — | — | US | disclosed |