SCHEMBL722938

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL724001	0.87	PDE4C (0.41)	PDE4CFYNBRD4CYP1A1CYP1B1
	SCHEMBL724037	0.84	RPS6KA2 (0.43)	PDE4CADORA2ABRD4CYP1A1CYP1B1
	SCHEMBL723093	0.83	PDE4C (0.55)	PDE4CFYNBRD4CYP1A1CYP1B1
	SCHEMBL722271	0.82	PDE4C (0.48)	PDE4CADORA2AFYNBRD4CYP1A1
	SCHEMBL724141	0.82	PDE4C (0.48)	PDE4CADORA2ABRD4CYP1A1CYP1B1
	SCHEMBL722596	0.82	PDE4C (0.50)	PDE4CADORA2AFYNBRD4CYP1A1
	SCHEMBL722937	0.81	FYN (0.48)	PDE4CADORA2AFYNBRD4CYP1A1
	SCHEMBL16638610	0.80	PDE4C (0.47)	PDE4CBRD4CYP1A1CYP1B1CYP1A2
	SCHEMBL15212572	0.80	BRD4 (0.47)	PDE4CFYNBRD4CYP1A1CYP1B1
	SCHEMBL723027	0.80	PTGES (0.47)	PDE4CBRD4CYP1A1CYP1B1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.