SCHEMBL7229649

SCHEMBL7229649

CCCC=Cc1ccc(CCCc2cc(F)c(F)c(F)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNNC1 P63316 1/20 0.41
SPHK1 Q9NYA1 2/20 0.34
RARB P10826 3/20 0.33
HTR2A P28223 1/20 0.33
SPHK2 Q9NRA0 1/20 0.33
RARA P10276 1/20 0.33
RARG P13631 1/20 0.33
TUBB1 Q9H4B7 1/20 0.33
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
TRPM2 O94759 1/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7229643 1.00 TNNC1 (0.41) TNNC1SPHK1RARBHTR2ASPHK2
SCHEMBL7230125 0.97 TNNC1 (0.41) TNNC1SPHK1RARBHTR2ASPHK2
SCHEMBL7230128 0.97 TNNC1 (0.41) TNNC1SPHK1RARBHTR2ASPHK2
SCHEMBL7237072 0.94 TNNC1 (0.40) TNNC1SPHK1TUBB1CYP4F2CYP4A11
SCHEMBL7237074 0.94 TNNC1 (0.40) TNNC1SPHK1TUBB1CYP4F2CYP4A11
SCHEMBL7240443 0.88 TNNC1 (0.41) TNNC1SPHK1RARBHTR2ASPHK2
SCHEMBL7231757 0.88 TNNC1 (0.47) TNNC1SPHK1RARBHTR2ASPHK2
SCHEMBL7231752 0.88 TNNC1 (0.47) TNNC1SPHK1RARBHTR2ASPHK2
SCHEMBL7240444 0.88 TNNC1 (0.41) TNNC1SPHK1RARBHTR2ASPHK2
SCHEMBL7229360 0.87 TNNC1 (0.52) TNNC1SPHK1RARBHTR2ASPHK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6623810-B2 Refractive index anisotropy SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-09-23 US disclosed
US-20010050353-A1 Phenylacetylene compound, liquid crystal composition, and liquid crystal element produced with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-13 US disclosed
EP-0781827-B1 Liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL CO (JP) 2001-06-13 EP disclosed
US-6149837-A SUBSTITUTED 1,4-BIS(SUBSTITUED PHENYLACETYLENE)BENZENE WHERE AT LEAST ONE RING HAS AN ALKYL ATTACHMENT, HAS A LARGE ANISOTROPY OF REFRACTIVE INDEX, TENDS TO BE MIXED WITH OTHER LIQUID CRYSTALS, IS LIGHT STABLE; LIQUID CRYSTAL ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-11-21 US disclosed
US-5866035-A LARGE BIREFRINGENCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-02 US disclosed
EP-0781827-A1 Liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-02 EP disclosed