Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2059427 | 1.00 | TLR7 (0.48) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL4670100 | 0.86 | TLR7 (0.61) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL10588025 | 0.86 | TLR7 (0.61) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL7229671 | 0.81 | MEN1 (0.47) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL7240083 | 0.81 | MEN1 (0.47) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL4380570 | 0.78 | MEN1 (0.40) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL4378168 | 0.78 | MEN1 (0.40) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL4380193 | 0.75 | TLR7 (0.38) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL13588439 | 0.75 | TLR7 (0.38) | TLR7ADORA2ALMNAPOLBHRH2 | |
| Epetirimod SCHEMBL29350668 | 0.74 | TLR7 (0.70) | TLR7ADORA2ALMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624172-B2 | Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor, and useful as viricides and antitumor agents | 3M INNOVATIVE PROPERTIES COMPANY | 2003-09-23 | — | — | US | claimed |