Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HRH2 | P25021 | 1/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588025 | 1.00 | TLR7 (0.61) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL13770893 | 0.87 | TLR7 (0.65) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL22749239 | 0.86 | TLR7 (0.64) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL22749238 | 0.86 | TLR7 (0.64) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL29508403 | 0.86 | TLR7 (0.64) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL22761517 | 0.86 | TLR7 (0.64) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL7229665 | 0.86 | TLR7 (0.48) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL2059427 | 0.86 | TLR7 (0.48) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL10589023 | 0.84 | MEN1 (0.51) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL22761521 | 0.83 | TLR7 (0.60) | TLR7ADORA2ALMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719511-B1 | N-[4-(4-amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamide, a pharmaceutical composition comprising the same and use thereof | 3M INNOVATIVE PROPERTIES CO (US) | 2008-12-10 | — | — | EP | disclosed |
| EP-1719511-A2 | N-[4-(4-amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamide, a pharmaceutical composition comprising the same and use thereof | 3M Innovative Properties Company (US) | 2006-11-08 | — | — | EP | disclosed |