Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8254544 | 1.00 | RNPEP (0.47) | RNPEPALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL30642009 | 1.00 | RNPEP (0.47) | RNPEPALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL29561871 | 1.00 | RNPEP (0.47) | RNPEPALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL8928051 | 0.88 | RNPEP (0.54) | RNPEPALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL15592739 | 0.86 | LMNA (0.51) | RNPEPALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL9911535 | 0.86 | LMNA (0.51) | RNPEPALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL9194550 | 0.83 | RNPEP (0.55) | RNPEPALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL5869722 | 0.81 | FOLH1 (0.58) | RNPEPALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL8248682 | 0.81 | FOLH1 (0.58) | RNPEPALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL8255575 | 0.81 | RNPEP (0.47) | RNPEPALDH1A1KDM4EL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6632830-B1 | Blood pressure related disease or disorder, cell proliferation disorder, kidney disorder, kinetensin associated disorder, inflammation associated disorder, or an allergic disorder | MILLENNIUM PHARMACEUTICALS, INC. | 2003-10-14 | — | — | US | disclosed |