Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 9/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229741 | 1.00 | OPRL1 (0.48) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL7228391 | 0.87 | OPRL1 (0.48) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL7230266 | 0.85 | OPRL1 (0.44) | OPRL1OPRM1 | |
| SCHEMBL7229847 | 0.83 | OPRL1 (0.42) | OPRL1OPRM1 | |
| SCHEMBL7228623 | 0.83 | OPRL1 (0.44) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL6617335 | 0.81 | OPRL1 (0.41) | OPRL1OPRM1CYP1A2CYP2D6TSHR | |
| SCHEMBL7221508 | 0.79 | OPRL1 (0.43) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL6613896 | 0.77 | OPRL1 (0.37) | OPRL1OPRM1 | |
| SCHEMBL6573291 | 0.77 | OPRL1 (0.38) | OPRL1 | |
| SCHEMBL6574374 | 0.77 | OPRL1 (0.38) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6573275-B1 | Insecticidal compositions comprising and to methods of combatting and controlling insect pests therewith. | SYNGENTA LIMITED (GB) | 2003-06-03 | — | — | US | disclosed |
| US-6207676-B1 | Bicyclic amines | ZENECA LIMITED (GB) | 2001-03-27 | — | — | US | disclosed |