Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6617335 | 0.86 | OPRL1 (0.41) | OPRL1SLC6A4SLC6A3CYP11B2CYP11B1 | |
| SCHEMBL7230196 | 0.86 | OPRL1 (0.38) | OPRL1SLC6A4SLC6A3CYP11B2CYP11B1 | |
| SCHEMBL6574374 | 0.86 | OPRL1 (0.38) | OPRL1SLC6A4SLC6A3CYP11B2CYP11B1 | |
| SCHEMBL8184433 | 0.86 | OPRL1 (0.36) | OPRL1CYP11B2CYP11B1 | |
| SCHEMBL8174171 | 0.86 | OPRL1 (0.36) | OPRL1CYP11B2CYP11B1 | |
| SCHEMBL7690570 | 0.84 | CYP11B2 (0.31) | CYP11B2CYP11B1 | |
| SCHEMBL7222791 | 0.84 | OPRL1 (0.35) | OPRL1 | |
| SCHEMBL7222052 | 0.84 | OPRL1 (0.35) | OPRL1CYP11B2CYP11B1 | |
| SCHEMBL7223809 | 0.84 | GRM5 (0.36) | OPRL1SLC6A4SLC6A3CYP11B2 | |
| SCHEMBL6573280 | 0.83 | SLC6A4 (0.37) | OPRL1SLC6A4SLC6A3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901490-B1 | BICYCLIC AMINES AS INSECTICIDES | SYNGENTA LTD (GB) | 2004-04-07 | — | — | EP | disclosed |
| EP-0901490-A1 | BICYCLIC AMINES AS INSECTICIDES | ZENECA LIMITED (GB) | 1999-03-17 | — | — | EP | disclosed |
| US-5859024-A | PESTICIDES | ZENECA LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| WO-1997043286-A1 | BICYCLIC AMINES AS INSECTICIDES | ZENECA LIMITED (GB) | 1997-11-20 | — | — | WO | disclosed |