Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28094251 | 0.93 | MEN1 (0.47) | CYP1A2ALDH1A1ALOX12HIF1APHLPP2 | |
| SCHEMBL7913584 | 0.81 | HSD17B10 (0.47) | CYP1A2ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL28379153 | 0.81 | HDAC4 (0.57) | CYP1A2ALDH1A1ALOX12HIF1APHLPP2 | |
| SCHEMBL14134243 | 0.79 | ACACA (0.49) | CYP1A2ALDH1A1MEN1KMT2AACACA | |
| SCHEMBL10897509 | 0.79 | PRKAA2 (0.46) | CYP1A2ALDH1A1HSD17B10MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL23044731 | 0.78 | MAPT (0.53) | CYP1A2ALDH1A1MEN1KMT2AHDAC4 | |
| Acetic Acid SCHEMBL28094250 | 0.78 | HSD17B10 (0.46) | CYP1A2ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9857357 | 0.77 | ABCG2 (0.50) | CYP1A2KMT2AHDAC4HDAC2HDAC8 | |
| SCHEMBL2202984 | 0.77 | MEN1 (0.45) | CYP1A2ALDH1A1MEN1KMT2AHDAC4 | |
| SCHEMBL1890032 | 0.76 | PPARG (0.56) | CYP1A2HDAC4HDAC2HDAC8ACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610705-B1 | Treating breast cancer, osteoporosis, hypercholesteremia or endometriosis | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-08-26 | — | — | US | disclosed |