SCHEMBL7230210

SCHEMBL7230210

CCC/C=C/c1ccc(CCc2cc(F)c(CCCCC)c(F)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNNC1 P63316 1/20 0.44
HTR2A P28223 1/20 0.37
TRPM2 O94759 3/20 0.37
RARB P10826 3/20 0.36
SPHK2 Q9NRA0 1/20 0.36
SPHK1 Q9NYA1 1/20 0.36
RARA P10276 1/20 0.36
RARG P13631 1/20 0.36
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
NPC1 O15118 1/20 0.34
HPGD P15428 1/20 0.34
CASP3 P42574 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
ESR1 P03372 2/20 0.34
ADRA2A P08913 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7230215 1.00 TNNC1 (0.44) TNNC1HTR2ATRPM2RARBSPHK2
SCHEMBL7236854 0.96 TNNC1 (0.42) TNNC1HTR2ATRPM2RARBSPHK2
SCHEMBL7236859 0.96 TNNC1 (0.42) TNNC1HTR2ATRPM2RARBSPHK2
SCHEMBL7233371 0.90 TNNC1 (0.40) TNNC1HTR2ATRPM2RARBSPHK2
SCHEMBL7233365 0.90 TNNC1 (0.40) TNNC1HTR2ATRPM2RARBSPHK2
SCHEMBL7228583 0.90 TNNC1 (0.39) TNNC1KDM4EALDH1A1NPC1HPGD
SCHEMBL7228587 0.90 TNNC1 (0.39) TNNC1KDM4EALDH1A1NPC1HPGD
SCHEMBL7232452 0.89 TNNC1 (0.50) TNNC1HTR2ARARBSPHK2SPHK1
SCHEMBL7232455 0.89 TNNC1 (0.50) TNNC1HTR2ARARBSPHK2SPHK1
SCHEMBL7228490 0.88 TNNC1 (0.45) TNNC1HTR2ARARBSPHK2SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6623810-B2 Refractive index anisotropy SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-09-23 US disclosed
US-20010050353-A1 Phenylacetylene compound, liquid crystal composition, and liquid crystal element produced with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-13 US disclosed
EP-0781827-B1 Liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL CO (JP) 2001-06-13 EP disclosed
US-6149837-A SUBSTITUTED 1,4-BIS(SUBSTITUED PHENYLACETYLENE)BENZENE WHERE AT LEAST ONE RING HAS AN ALKYL ATTACHMENT, HAS A LARGE ANISOTROPY OF REFRACTIVE INDEX, TENDS TO BE MIXED WITH OTHER LIQUID CRYSTALS, IS LIGHT STABLE; LIQUID CRYSTAL ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-11-21 US disclosed
US-5866035-A LARGE BIREFRINGENCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-02 US disclosed
EP-0781827-A1 Liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-02 EP disclosed