Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LIG1 | P18858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3820950 | 0.82 | HPGD (0.54) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL2317921 | 0.81 | HPGD (0.71) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL2664412 | 0.80 | CA12 (0.47) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL7228644 | 0.79 | IDO1 (0.55) | HPGDALDH1A1MAPTLMNAALOX12 | |
| SCHEMBL2650002 | 0.79 | IDO1 (0.37) | HPGDTSHRMAPK1ALDH1A1MEN1 | |
| SCHEMBL7239605 | 0.79 | PLAU (0.48) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL2658430 | 0.78 | NPC1 (0.39) | HPGDHSD17B10ALDH1A1CA12CA9 | |
| SCHEMBL2650195 | 0.78 | CA12 (0.44) | HPGDTSHRALDH1A1CA12CA9 | |
| SCHEMBL26208701 | 0.76 | HPGD (0.45) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL20554524 | 0.76 | IDO1 (0.52) | HPGDTSHRMAPK1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |