Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235370 | 0.89 | CCR5 (0.44) | PLAUPLATRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2650838 | 0.85 | HTR1A (0.46) | PLAUPLATMAPTALDH1A1POLB | |
| SCHEMBL7237910 | 0.83 | ABCB1 (0.49) | SMN1; SMN2MAPTHTTMRGPRX4 | |
| SCHEMBL2649711 | 0.83 | GCGR (0.56) | PLAUPLATRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7235286 | 0.82 | TACR1 (0.42) | MAPTL3MBTL1ALDH1A1POLBGAA | |
| SCHEMBL16230494 | 0.81 | ALDH1A1 (0.61) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL7227813 | 0.80 | GCGR (0.47) | PLAUPLATGCGRMRGPRX4MAPK14 | |
| SCHEMBL7228342 | 0.80 | ALDH1A1 (0.37) | PLAUPLATRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7235343 | 0.80 | ALDH1A1 (0.52) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL416462 | 0.80 | MAPT (0.57) | PLAUPLATRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |