Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | APOL1 | O14791 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7234870 | 0.93 | TSPO (0.61) | TSPOALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL7233607 | 0.91 | TSPO (0.59) | TSPOALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL7230765 | 0.87 | TSPO (0.52) | TSPOALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL7241810 | 0.85 | CXCR2 (0.56) | TSPOTACR1PPARGCXCR2 | |
| SCHEMBL7232536 | 0.85 | TSPO (0.49) | TSPOALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL7242328 | 0.84 | PPARG (0.61) | TSPOALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL7233766 | 0.82 | PPARG (0.58) | TSPOALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL28750582 | 0.81 | TSPO (0.56) | TSPOALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL27568267 | 0.81 | TSPO (0.46) | TSPOALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL27568193 | 0.81 | PPARG (0.57) | TSPOALDH1A1CYP1A2HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605633-B1 | Such as 5-Bromo-2-phenyl-1H-indole-3-butanoic acid | FOURNIER INDUSTRIE ET SANTE (FR) | 2003-08-12 | — | — | US | disclosed |