Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7231075 | 1.00 | KDM4E (0.46) | KDM4ELMNAALDH1A1THRBHPGD | |
| SCHEMBL17165987 | 0.85 | KDM4E (0.45) | KDM4ELMNAALDH1A1THRBHPGD | |
| SCHEMBL4741806 | 0.80 | KDM4E (0.53) | KDM4ELMNAALDH1A1THRBHPGD | |
| SCHEMBL17165986 | 0.80 | KDM4E (0.42) | KDM4ELMNAALDH1A1THRBHPGD | |
| SCHEMBL7231695 | 0.78 | KDM4E (0.37) | KDM4ELMNAALDH1A1 | |
| SCHEMBL169821 | 0.78 | KDM4E (0.44) | KDM4ELMNAALDH1A1THRBHPGD | |
| SCHEMBL13346338 | 0.77 | KDM4E (0.50) | KDM4ELMNAALDH1A1THRBHPGD | |
| SCHEMBL17165984 | 0.77 | KDM4E (0.41) | KDM4ELMNAALDH1A1THRBHPGD | |
| SCHEMBL14581091 | 0.76 | KDM4E (0.62) | KDM4ELMNAALDH1A1THRBHPGD | |
| SCHEMBL32689006 | 0.75 | KDM4E (0.51) | KDM4ELMNAALDH1A1THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518305-B1 | For inhibiting neuraminidases from disease- causing microorganisms, especially, influenza neuraminidase | ABBOTT LABORATORIES | 2003-02-11 | — | — | US | disclosed |
| WO-2001028979-A2 | INHIBITORS OF NEURAMINIDASES | ABBOTT LABORATORIES (US) | 2001-04-26 | — | — | WO | disclosed |