SCHEMBL4741806

SCHEMBL4741806

CCC(=O)C1CC2C=CC1C2

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.53
LMNA P02545 1/20 0.53
THRB P10828 1/20 0.38
EPHX2 P34913 3/20 0.38
ALDH1A1 P00352 6/20 0.37
HPGD P15428 1/20 0.37
KMT2A Q03164 2/20 0.36
POLB P06746 2/20 0.36
RAB9A P51151 1/20 0.36
APEX1 P27695 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
ESR2 Q92731 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32689006 0.85 KDM4E (0.51) KDM4ELMNATHRBEPHX2ALDH1A1
SCHEMBL13346338 0.85 KDM4E (0.50) KDM4ELMNATHRBEPHX2ALDH1A1
SCHEMBL32689208 0.84 KDM4E (0.46) KDM4ELMNATHRBEPHX2ALDH1A1
SCHEMBL14581091 0.83 KDM4E (0.62) KDM4ELMNATHRBEPHX2ALDH1A1
SCHEMBL13346339 0.82 LMNA (0.47) KDM4ELMNATHRBEPHX2ALDH1A1
SCHEMBL32689204 0.81 KDM4E (0.55) KDM4ELMNATHRBEPHX2ALDH1A1
SCHEMBL7230937 0.80 KDM4E (0.46) KDM4ELMNATHRBEPHX2ALDH1A1
SCHEMBL17165985 0.80 KDM4E (0.46) KDM4ELMNATHRBEPHX2ALDH1A1
SCHEMBL7231075 0.80 KDM4E (0.46) KDM4ELMNATHRBEPHX2ALDH1A1
SCHEMBL11708853 0.80 KDM4E (0.53) KDM4ELMNATHRBEPHX2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210246266-A1 HIGH DYNAMIC RANGE TWO-STAGE PHOTOPOLYMERS NATIONAL SCIENCE FOUNDATION 2021-08-12 US disclosed
US-20200115400-A1 METHOD FOR PRODUCING SILICON COMPOUND, AND SILICON COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-04-16 US disclosed
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2017-11-02 US disclosed
EP-1415974-B1 PROCESS FOR PRODUCTION OF FLUORINE-CONTAINING NORBORNENE DERIVATIVES DAIKIN IND LTD (JP) 2017-03-01 EP disclosed
US-20160311970-A1 INSERTION POLYNORBORNENE-BASED THERMOSET RESINS CLAVERIE, Jérôme (CA) 2016-10-27 US disclosed
EP-2031007-B1 Top-coat compositions with norbornene-type polymers and immersion lithographic processes using such compositions TOKYO OHKA KOGYO CO LTD (JP) 2011-07-20 EP disclosed
US-7649118-B2 Process for preparing fluorine-containing norbornene derivative DAIKIN INDUSTRIES, LTD. (JP) 2010-01-19 US disclosed
US-20080199805-A1 PHOTOSENSITIVE COMPOSITIONS EMPLOYING SILICON-CONTAINING ADDITIVES FUJIFILM ELECTRONIC MATERIALS. U.S.A., INC. 2008-08-21 US disclosed
WO-2008098189-A1 PHOTOSENSITIVE COMPOSITIONS EMPLOYING SILICON-CONTAINING ADDITIVES FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2008-08-14 WO disclosed
US-20070194301-A1 Semiconductor arrangement with non-volatile memories INFINEON TECHNOLOGIES AG (DE) 2007-08-23 US disclosed
US-20070164276-A1 Method for Forming Memory Layers QIMONDA AG (DE) 2007-07-19 US disclosed
US-7205086-B2 Multilayer elements containing photoresist compositions and their use in microlithography E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200115400-A1 METHOD FOR PRODUCING SILICON COMPOUND, AND SILICON COMPOUND SI, SIK1, CA1 KDM4E 3666/4885LMNA 3637/4885THRB 4711/4885
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR HDGF, F11, F12 KDM4E 4115/4885LMNA 826/4885THRB 3592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.