SCHEMBL7230997

SCHEMBL7230997

C=C(C)n1c(=O)[nH]c2cc(F)ccc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 6/20 0.59
FEN1 P39748 2/20 0.45
GABRP O00591 3/20 0.42
GABRD O14764 3/20 0.42
GABRA1 P14867 3/20 0.42
GABRB1 P18505 3/20 0.42
GABRG2 P18507 3/20 0.42
GABRB3 P28472 3/20 0.42
GABRA5 P31644 3/20 0.42
GABRA3 P34903 3/20 0.42
GABRA2 P47869 3/20 0.42
GABRB2 P47870 3/20 0.42
GABRA4 P48169 3/20 0.42
GABRE P78334 3/20 0.42
GABRA6 Q16445 3/20 0.42
GABRG1 Q8N1C3 3/20 0.42
GABRG3 Q99928 3/20 0.42
GABRQ Q9UN88 3/20 0.42
KDM4E B2RXH2 1/20 0.40
PGR P06401 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7224406 0.88 DAO (0.59) DAOFEN1GABRPGABRDGABRA1
SCHEMBL11197239 0.83 DAO (0.61) DAODDO
SCHEMBL14906711 0.81 MEN1 (0.50) DAOPGRPLD1
SCHEMBL8947414 0.81 DAO (0.63) DAOFEN1GABRPGABRDGABRA1
SCHEMBL8570527 0.81 HSP90AA1 (0.54) DAO
SCHEMBL29356336 0.77 DAO (0.55) DAO
SCHEMBL507863 0.77 DAO (0.55) DAO
SCHEMBL14906718 0.77 SIRT2 (0.51) DAOPGR
SCHEMBL8630817 0.76 LMNA (0.58) DAOKDM4EPGR
SCHEMBL21464105 0.76 DAO (0.52) DAOFEN1GABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114369903-B Ageing-resistant hydrophilic non-woven fabric and preparation method thereof 宁波捷傲创益新材料有限公司 2023-06-02 CN claimed
CN-116179972-A High-strength automobile fastener 宁波合鑫标准件有限公司 2023-05-30 CN claimed
CN-114369903-A Anti-aging hydrophilic non-woven fabric and preparation method thereof 宁波捷傲创益新材料有限公司 2022-04-19 CN claimed
CN-117569082-A Ageing-resistant hydrophilic non-woven fabric and preparation method thereof 扬州新科展纺织制品有限公司 2024-02-20 CN disclosed
CN-114369903-B Ageing-resistant hydrophilic non-woven fabric and preparation method thereof 宁波捷傲创益新材料有限公司 2023-06-02 CN disclosed
CN-114369903-B Ageing-resistant hydrophilic non-woven fabric and preparation method thereof 宁波捷傲创益新材料有限公司 2023-06-02 CN disclosed
CN-116179972-A High-strength automobile fastener 宁波合鑫标准件有限公司 2023-05-30 CN disclosed
CN-114369903-A Anti-aging hydrophilic non-woven fabric and preparation method thereof 宁波捷傲创益新材料有限公司 2022-04-19 CN disclosed
CN-114369903-A Anti-aging hydrophilic non-woven fabric and preparation method thereof 宁波捷傲创益新材料有限公司 2022-04-19 CN disclosed
US-6506738-B1 Treatment of viral infections. More particularly, the invention provides benzimidazolone derivatives for the treatment of respiratory syncytial virus infection. BRISTOL-MYERS SQUIBB COMPANY 2003-01-14 US disclosed
WO-2002026228-A1 BENZIMIDAZOLONE ANTIVIRAL AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 2002-04-04 WO disclosed