Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 4/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.44 |
| ▸ | HTR3B | O95264 | 4/20 | 0.44 |
| ▸ | HTR3A | P46098 | 4/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7232673 | 0.89 | MAPK11 (0.49) | ESRRGESR1ESR2PTPN1PTPN11 | |
| SCHEMBL7224991 | 0.89 | ESRRG (0.46) | ESRRGESR1ESR2PTPN1PTPN11 | |
| SCHEMBL7223338 | 0.88 | CHRNA7 (0.57) | ESRRGESR1ESR2PTPN1PTPN11 | |
| SCHEMBL375517 | 0.88 | CHRNA7 (0.57) | ESRRGESR1ESR2PTPN1PTPN11 | |
| SCHEMBL7243634 | 0.88 | CHRNA7 (0.42) | ESRRGESR1ESR2PTPN1PTPN11 | |
| SCHEMBL7243631 | 0.88 | CHRNA7 (0.42) | ESRRGESR1ESR2PTPN1PTPN11 | |
| SCHEMBL7223964 | 0.88 | CHRNA7 (0.42) | ESRRGESR1ESR2PTPN1PTPN11 | |
| SCHEMBL7232519 | 0.87 | MAPK11 (0.48) | ESRRGESR1ESR2PTPN1PTPN11 | |
| SCHEMBL7224563 | 0.87 | PTPN1 (0.49) | ESRRGESR1ESR2PTPN1PTPN11 | |
| SCHEMBL7223923 | 0.87 | PTPN11 (0.49) | ESRRGESR1ESR2PTPN1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |