Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC8A1 | P32418 | 13/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7231617 | 0.90 | SLC8A1 (0.48) | SLC8A1 | |
| SCHEMBL7117176 | 0.84 | SLC8A1 (0.38) | SLC8A1 | |
| SCHEMBL7122435 | 0.84 | CHRNA7 (0.36) | SLC8A1SLC6A4SLC6A3 | |
| SCHEMBL7234386 | 0.83 | SLC6A4 (0.40) | CCNCCDK8SLC6A4SLC6A3 | |
| SCHEMBL7229535 | 0.83 | SLC6A4 (0.40) | CCNCCDK8SLC6A4SLC6A3 | |
| SCHEMBL7225066 | 0.82 | SLC6A4 (0.41) | CCNCCDK8SLC6A4SLC6A3 | |
| SCHEMBL7231198 | 0.82 | SMN1; SMN2 (0.47) | SLC6A4SLC6A3 | |
| SCHEMBL7222700 | 0.80 | SLC6A4 (0.37) | SLC6A4SLC6A3 | |
| SCHEMBL7125243 | 0.80 | ALDH1A1 (0.38) | SLC8A1SLC6A4SLC6A3 | |
| SCHEMBL7124966 | 0.80 | SLC6A4 (0.46) | SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |