Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.61 |
| ▸ | PTAFR | P25105 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901283 | 0.86 | GRM1 (0.47) | GRM1PTAFRHPGDALDH1A1MAPT | |
| SCHEMBL6901288 | 0.86 | GRM1 (0.47) | GRM1PTAFRHPGDALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7235500 | 0.84 | ALDH1A1 (0.66) | GRM1PTAFRHPGDALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7235509 | 0.84 | MAPT (0.58) | GRM1HPGDALDH1A1MAPTKLK7 | |
| Hydrochloric Acid SCHEMBL7232026 | 0.82 | GRM1 (0.72) | GRM1PTAFRHPGDALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7232011 | 0.82 | GRM1 (0.62) | GRM1PTAFRHPGDALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7233116 | 0.81 | GRM1 (0.71) | GRM1PTAFRHPGDALDH1A1MAPT | |
| SCHEMBL7232093 | 0.81 | GRM1 (0.54) | GRM1HPGDALDH1A1MAPTKLK7 | |
| Hydrochloric Acid SCHEMBL7233125 | 0.81 | GRM1 (0.61) | GRM1PTAFRHPGDALDH1A1MAPT | |
| SCHEMBL7232085 | 0.81 | GRM1 (0.61) | GRM1HPGDALDH1A1MAPTKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642264-B1 | Thiazolo(3,2-a)benzoimidazole derivatives act specifically on metabotropic glutamate receptors and are used as medicaments. | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| EP-1167369-A1 | NOVEL THIAZOLOBENZIMIDAZOLE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |