SCHEMBL7232180

SCHEMBL7232180

OCCOCCOC(COCC1CO1)CC1CO1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
TSHR P16473 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPK1 P28482 2/20 0.32
PDK1 Q15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18183255 0.91 TSHR (0.40) ALDH1A1TSHRSMN1; SMN2TDP1MEN1
SCHEMBL28285401 0.80 ALDH1A1 (0.46) ALDH1A1TSHRSMN1; SMN2TDP1MAPK1
Water SCHEMBL15797971 0.79 ALDH1A1 (0.45) ALDH1A1TSHRSMN1; SMN2TDP1MAPK1
SCHEMBL13681581 0.78 TSHR (0.40) ALDH1A1TSHRSMN1; SMN2TDP1MAPK1
SCHEMBL27944755 0.78 MEN1 (0.35) ALDH1A1TSHRSMN1; SMN2TDP1MEN1
SCHEMBL4608703 0.78 TSHR (0.60) ALDH1A1TSHRSMN1; SMN2TDP1MEN1
SCHEMBL8191937 0.78 TSHR (0.60) ALDH1A1TSHRSMN1; SMN2TDP1MEN1
SCHEMBL29212545 0.78 TSHR (0.60) ALDH1A1TSHRSMN1; SMN2TDP1MEN1
SCHEMBL4976681 0.78 TSHR (0.60) ALDH1A1TSHRSMN1; SMN2TDP1MEN1
SCHEMBL8198631 0.78 TSHR (0.60) ALDH1A1TSHRSMN1; SMN2TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6653484-B2 Triazine, benzotriazole, or benzophenone-type stabilizers conjugated to polyoxyalkylene groups; use as ultraviolet radiation absorbers in photographic materials CIBA SPECIALTY CHEMICALS CORPORATION 2003-11-25 US disclosed
EP-1266889-A2 Polyoxyalkylene substituted and bridged triazine and benzotriazole derivatives Ciba SC Holding AG (CH) 2002-12-18 EP disclosed
US-6369267-B1 RADIATION RESISTANCE TO ULTRAVIOLET RADIATION CIBA SPECIALTY CHEMICALS CORPORATION 2002-04-09 US disclosed
EP-0912531-A1 POLYOXYALKENE SUBSTITUTED AND BRIDGED TRIAZINE, BENZOTRIAZOLE AND BENZOPHENONE DERIVATIVES AS UV ABSORBERS Ciba SC Holding AG (CH) 1999-05-06 EP disclosed
WO-1998003489-A1 POLYOXYALKENE SUBSTITUTED AND BRIDGED TRIAZINE, BENZOTRIAZOLE AND BENZOPHENONE DERIVATIVES AS UV ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-01-29 WO disclosed