SCHEMBL7232467

SCHEMBL7232467

CCCC=Cc1ccc(CCc2ccc(CCCC)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNNC1 P63316 1/20 0.51
SPHK1 Q9NYA1 2/20 0.46
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
GRIN1 Q05586 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIN2B Q13224 1/20 0.44
GRIN2C Q14957 1/20 0.44
GRIN3A Q8TCU5 1/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CA2 P00918 2/20 0.43
CA1 P00915 1/20 0.43
ALDH1A1 P00352 3/20 0.42
HPGD P15428 3/20 0.42
HSD17B10 Q99714 2/20 0.42
SPHK2 Q9NRA0 1/20 0.41
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7232465 1.00 TNNC1 (0.51) TNNC1SPHK1GRIN2DGRIN3BGRIN1
SCHEMBL7236848 0.95 TNNC1 (0.54) TNNC1SPHK1CYP3A4CYP2D6CYP2C9
SCHEMBL7236849 0.95 TNNC1 (0.54) TNNC1SPHK1CYP3A4CYP2D6CYP2C9
SCHEMBL7233382 0.93 TNNC1 (0.56) TNNC1SPHK1CYP3A4CYP2D6CYP2C9
SCHEMBL7229266 0.93 TNNC1 (0.56) TNNC1SPHK1CYP3A4CYP2D6CYP2C9
SCHEMBL7231480 0.93 TNNC1 (0.56) TNNC1SPHK1CYP3A4CYP2D6CYP2C9
SCHEMBL7229271 0.93 TNNC1 (0.56) TNNC1SPHK1CYP3A4CYP2D6CYP2C9
SCHEMBL7237390 0.93 TNNC1 (0.56) TNNC1SPHK1CYP3A4CYP2D6CYP2C9
SCHEMBL7237386 0.93 TNNC1 (0.56) TNNC1SPHK1CYP3A4CYP2D6CYP2C9
SCHEMBL7236757 0.93 TNNC1 (0.56) TNNC1SPHK1CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6623810-B2 Refractive index anisotropy SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-09-23 US disclosed
US-20010050353-A1 Phenylacetylene compound, liquid crystal composition, and liquid crystal element produced with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-13 US disclosed
EP-0781827-B1 Liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL CO (JP) 2001-06-13 EP disclosed
US-6149837-A SUBSTITUTED 1,4-BIS(SUBSTITUED PHENYLACETYLENE)BENZENE WHERE AT LEAST ONE RING HAS AN ALKYL ATTACHMENT, HAS A LARGE ANISOTROPY OF REFRACTIVE INDEX, TENDS TO BE MIXED WITH OTHER LIQUID CRYSTALS, IS LIGHT STABLE; LIQUID CRYSTAL ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-11-21 US disclosed
US-5866035-A LARGE BIREFRINGENCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-02 US disclosed
EP-0781827-A1 Liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-02 EP disclosed