Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 10/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725880 | 0.89 | ADORA2A (0.57) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL5034543 | 0.84 | ADORA1 (0.58) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL465954 | 0.84 | ADORA2A (0.56) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL7394674 | 0.84 | ADORA2A (0.56) | ADORA2AADORA2BADORA1ADORA3 | |
| Water SCHEMBL3630434 | 0.83 | ADORA2A (0.55) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL271079 | 0.82 | ADORA2A (0.61) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL5034075 | 0.78 | ADORA1 (0.55) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL6582202 | 0.78 | ADORA3 (0.54) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL272093 | 0.78 | ADORA2A (0.69) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL5032115 | 0.78 | ADORA1 (0.56) | ADORA2AADORA2BADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2608794-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING OBESITY | Northeastern University (US) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012027695-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING OBESITY | NORTHEASTERN UNIVERSITY (US) | 2012-03-01 | — | — | WO | disclosed |
| WO-2010065959-A1 | METHOD OF PREPARING ADENOSINE-RESISTANT ANTI-TUMOR T LYMPHOCYTES FOR ADOPTIVE IMMUNOTHERAPY | NORTHEASTERN UNIVERSITY (US) | 2010-06-10 | — | — | WO | disclosed |