SCHEMBL7233258

SCHEMBL7233258

CC(=O)Oc1c(C)cc(N)cc1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.49
HSD17B10 Q99714 3/20 0.49
HTT P42858 2/20 0.49
GAA P10253 2/20 0.49
MAPT P10636 2/20 0.49
TP53 P04637 1/20 0.49
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
POLB P06746 1/20 0.42
CYP19A1 P11511 1/20 0.40
LMNA P02545 2/20 0.39
ACHE P22303 2/20 0.38
BACE1 P56817 1/20 0.38
PREP P48147 3/20 0.36
CELA1 Q9UNI1 2/20 0.36
TOP1 P11387 1/20 0.36
ABCB11 O95342 1/20 0.36
PDE10A Q9Y233 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9178766 0.98 KDM4E (0.47) KDM4EHSD17B10HTTGAAMAPT
SCHEMBL22443160 0.87 HTT (0.42) KDM4EHSD17B10HTTGAAMAPT
SCHEMBL3156904 0.82 KDM4E (0.52) KDM4EHSD17B10HTTGAAMAPT
SCHEMBL23809728 0.80 BACE1 (0.52) KDM4EHSD17B10HTTGAAMAPT
SCHEMBL3600800 0.80 HSD17B10 (0.55) KDM4EHSD17B10HTTGAAMAPT
SCHEMBL7384263 0.78 KDM4E (0.49) KDM4EHSD17B10HTTGAAMAPT
SCHEMBL10790928 0.78 HTT (0.49) KDM4EHSD17B10HTTGAAMAPT
SCHEMBL12299731 0.78 KDM4E (0.49) KDM4EHSD17B10HTTGAAMAPT
SCHEMBL9042745 0.78 KDM4E (0.49) KDM4EHSD17B10HTTGAAMAPT
SCHEMBL8041869 0.78 KDM4E (0.49) KDM4EHSD17B10HTTGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117164745-A Composite material for microporous membrane, composite ion exchange membrane and application of composite material 国家电投集团氢能科技发展有限公司 2023-12-05 CN claimed
CN-117126311-A Polymer, composite, ion exchange membrane and preparation method and application thereof 国家电投集团氢能科技发展有限公司 2023-11-28 CN claimed
CN-116808842-B Modified microporous membrane, composite ion exchange membrane, and preparation methods and applications thereof 国家电投集团氢能科技发展有限公司 2023-10-27 CN claimed
CN-116808842-A Modified microporous membrane, composite ion exchange membrane, and preparation methods and applications thereof 国家电投集团氢能科技发展有限公司 2023-09-29 CN claimed
CN-117164745-A Composite material for microporous membrane, composite ion exchange membrane and application of composite material 国家电投集团氢能科技发展有限公司 2023-12-05 CN disclosed
CN-117126311-A Polymer, composite, ion exchange membrane and preparation method and application thereof 国家电投集团氢能科技发展有限公司 2023-11-28 CN disclosed
CN-116808842-B Modified microporous membrane, composite ion exchange membrane, and preparation methods and applications thereof 国家电投集团氢能科技发展有限公司 2023-10-27 CN disclosed
CN-116808842-A Modified microporous membrane, composite ion exchange membrane, and preparation methods and applications thereof 国家电投集团氢能科技发展有限公司 2023-09-29 CN disclosed
EP-1632479-B1 Pharmaceutical compositions comprising CCR5 antagonizing piperazine derivatives SCHERING CORP (US) 2011-01-12 EP disclosed
US-6599908-B1 Potent and selective inhibitors of the protein tyrosine kinases p56lck and p59fyn CELLTECH R & D LIMITED (GB) 2003-07-29 US disclosed
US-6057329-A Fused polycyclic 2-aminopyrimidine derivatives CELLTECH THERAPEUTICS LIMITED (GB) 2000-05-02 US disclosed
EP-0946523-A1 FUSED POLYCYCLIC 2-AMINOPYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEIN TYROSINE KINASE INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 1999-10-06 EP disclosed
EP-0481383-B1 Heterocyclic amine derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-06-28 EP disclosed
US-5428044-A Anti-inflammatory 4-aminophenyl derivatives FISONS PLC (GB) 1995-06-27 US disclosed
US-5300646-A Intermediates for acylcoenzyme A:cholesterol acyltransferase inhibitors TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-04-05 US disclosed
US-5198462-A Acyl Coenzyme A:Cholesterol Transferase Inhibitors TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-30 US disclosed
EP-0481383-A1 Heterocyclic amine derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1992-04-22 EP disclosed
EP-0425650-A1 ANTI-INFLAMMATORY 4-AMINOPHENOL DERIVATIVES. FISONS PLC (GB) 1991-05-08 EP disclosed
CN-1047497-A ANTI INFLAMMATORY AMINOPHENOL DERIVATIVES FISONS PLC (GB) 1990-12-05 CN disclosed
WO-1990014338-A1 ANTI-INFLAMMATORY 4-AMINOPHENOL DERIVATIVES FISONS PLC (GB) 1990-11-29 WO disclosed