Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672142 | 0.84 | KDM4E (0.44) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL11579831 | 0.84 | KDM4E (0.44) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL3600800 | 0.84 | HSD17B10 (0.55) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL23809728 | 0.84 | BACE1 (0.52) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL15509359 | 0.83 | RAPGEF4 (0.40) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL9042745 | 0.82 | KDM4E (0.49) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL7233258 | 0.82 | KDM4E (0.49) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL10790928 | 0.82 | HTT (0.49) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL12299731 | 0.82 | KDM4E (0.49) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL7384263 | 0.82 | KDM4E (0.49) | KDM4EHTTHSD17B10TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106431897-B | A kind of new synthesis process of 2,4,6- trimethylbenzene chloroacetic chloride | 宿迁科思化学有限公司 | 2019-06-04 | — | — | CN | claimed |
| CN-109020936-A | A kind of preparation method of Spiromesifen and its intermediate | 山东康乔生物科技有限公司 | 2018-12-18 | — | — | CN | claimed |
| CN-106431897-A | New compounding technology for 2,4,6-trimethyl phenylacetyl chloride | 宿迁科思化学有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-103880985-B | Hydrocarbon polymer is with dispersant and prepare the method for dispersion | SINOPEC CORP. (CN) | 2016-05-04 | — | — | CN | claimed |
| US-4212989-A | ARYL ESTER SOLVENTS USED IN CATALYTIC CARBONYLATION FO ALCOHOLS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1980-07-15 | — | — | US | claimed |
| US-11807716-B2 | Oligomer (2,6-dimethylphenylene ether) together with fabrication method and cured product thereof | CPC CORPORATION, TAIWAN (TW) | 2023-11-07 | — | — | US | disclosed |
| CN-106431897-B | A kind of new synthesis process of 2,4,6- trimethylbenzene chloroacetic chloride | 宿迁科思化学有限公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-109020936-A | A kind of preparation method of Spiromesifen and its intermediate | 山东康乔生物科技有限公司 | 2018-12-18 | — | — | CN | disclosed |
| CN-109020936-A | A kind of preparation method of Spiromesifen and its intermediate | 山东康乔生物科技有限公司 | 2018-12-18 | — | — | CN | disclosed |
| CN-107848988-A | Alkenyl substituted 2, 5-piperazinediones and their use in compositions for delivering an agent to a subject or cell | 麻省理工学院 | 2018-03-27 | — | — | CN | disclosed |
| EP-2148865-B1 | PYRAZOLE INHIBITORS OF WNT SIGNALING | GENENTECH INC (US) | 2017-05-17 | — | — | EP | disclosed |
| CN-104829418-B | Method for preparing benzyl chloride compound | 湖南海利化工股份有限公司 | 2017-05-17 | — | — | CN | disclosed |
| US-20070149574-A1 | Novel cyclic compound having 4-pyridylalkylthio group having substituted or unsubstituted amino group introduced therein | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2007-06-28 | — | — | US | disclosed |
| US-20070149574-A1 | Novel cyclic compound having 4-pyridylalkylthio group having substituted or unsubstituted amino group introduced therein | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2007-06-28 | — | — | US | disclosed |
| US-5905068-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1999-05-18 | — | — | US | disclosed |
| US-4381221-A | Process for recovering a reaction product while preventing decomposition of the catalyst | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1983-04-26 | — | — | US | disclosed |
| EP-0074837-A1 | 4-Substituted pyridine catalysts | REILLY TAR & CHEMICAL CORPORATION (US) | 1983-03-23 | — | — | EP | disclosed |
| US-4234733-A | PHENOL, ALIPHATIC ESTER OR ETHER, CARBON MONOXIDE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1980-11-18 | — | — | US | disclosed |
| US-4212989-A | ARYL ESTER SOLVENTS USED IN CATALYTIC CARBONYLATION FO ALCOHOLS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1980-07-15 | — | — | US | disclosed |
| US-4101391-A | Electrolytic oxidative methyl-methyl coupling of cresol salts | MONSANTO COMPANY (US) | 1978-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149574-A1 | Novel cyclic compound having 4-pyridylalkylthio group having substituted or unsubstituted amino group introduced therein | FLT4, FLT1, TIE1 | KDM4E 1390/4885HTT 2163/4885HSD17B10 2594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.