Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5080973 | 0.82 | PRKCI (0.55) | PRKCICYP2A6TUBB4ATUBBTUBA3C | |
| SCHEMBL30444309 | 0.82 | PRKCI (0.55) | PRKCICYP2A6TUBB4ATUBBTUBA3C | |
| SCHEMBL18314120 | 0.81 | PRKCI (0.53) | PRKCICYP2A6KDM4CKDRCHRNA7 | |
| SCHEMBL8685783 | 0.79 | PRKCI (0.52) | PRKCICYP2A6KDM4CKDRCHRNA7 | |
| SCHEMBL2656889 | 0.79 | PRKCI (0.52) | PRKCICYP2A6KDM4CKDRCHRNA7 | |
| SCHEMBL11009200 | 0.78 | MAPT (0.51) | PRKCICYP2A6KDRPPARDPPARA | |
| SCHEMBL26441685 | 0.78 | PRKCI (0.50) | PRKCICYP2A6KDM4CKDRCHRNA7 | |
| SCHEMBL5431673 | 0.77 | PRKCI (0.49) | PRKCICYP2A6KDM4CKDRCHRNA7 | |
| SCHEMBL16441025 | 0.77 | PRKCI (0.49) | PRKCICYP2A6KDM4CKDRCHRNA7 | |
| SCHEMBL7232110 | 0.77 | HTR2C (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642255-B2 | Substituted carbocyclic or heterocyclic hydroxamic acid derivatives, e.g., (3R,4S)-N-hydroxy-1-methyl-3-(((4-((2-methyl-4 -quinolinyl)methoxylphenyl)sulfonyl)methyl)-4-piperidinecarboxamide | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-11-04 | — | — | US | disclosed |