Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30444309 | 1.00 | PRKCI (0.55) | PRKCIHTR2CL3MBTL1CYP2A6POLB | |
| SCHEMBL29637256 | 0.85 | FAAH (0.58) | PRKCICYP2A6TUBB1TUBB4ATUBB | |
| SCHEMBL8685783 | 0.85 | PRKCI (0.52) | PRKCIHTR2CL3MBTL1CYP2A6POLB | |
| SCHEMBL3481643 | 0.84 | CYP11B1 (0.50) | PRKCIHTR2CL3MBTL1CYP2A6POLB | |
| SCHEMBL1093766 | 0.84 | HTR2A (0.57) | HTR2CCYP2A6HTR6MTNR1AMTNR1B | |
| SCHEMBL29869916 | 0.84 | HTR2A (0.57) | HTR2CCYP2A6HTR6MTNR1AMTNR1B | |
| SCHEMBL18314120 | 0.82 | PRKCI (0.53) | PRKCIHTR2CCYP2A6TUBB1TUBB4A | |
| SCHEMBL7233306 | 0.82 | PRKCI (0.53) | PRKCIHTR2CCYP2A6TUBB1TUBB4A | |
| SCHEMBL2656889 | 0.81 | PRKCI (0.52) | PRKCIHTR2CCYP2A6TUBB1TUBB4A | |
| SCHEMBL2981004 | 0.80 | NQO2 (0.58) | CYP2A6TUBB1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119409615-A | 2- (Indol-3-yl) phenol compound and synthesis method thereof | 湘潭大学 | 2025-02-11 | — | — | CN | claimed |
| CN-117903161-A | Tetrathiodiindole compound and derivative, synthetic method and application thereof | 衡阳师范学院 | 2024-04-19 | — | — | CN | claimed |
| EP-4267564-A1 | INDOLE DERIVATIVES USEFUL IN TREATING CONDITIONS ASSOCIATED WITH CGAS | Novartis AG (CH) | 2023-11-01 | — | — | EP | claimed |
| CN-116969967-A | Synthesis method of polysubstituted-5, 10-dihydro [1,2,3,4] tetrathio [5,6-b:7,8-b' ] diindole and derivative | 衡阳师范学院 | 2023-10-31 | — | — | CN | claimed |
| CN-116813639-A | Synthesis method of polysubstituted [1,2,3,4,5] pentathio [6,7-b ] indole and derivative | 衡阳师范学院 | 2023-09-29 | — | — | CN | claimed |
| WO-2022137085-A1 | INDOLE DERIVATIVES USEFUL IN TREATING CONDITIONS ASSOCIATED WITH CGAS | NOVARTIS AG (CH) | 2022-06-30 | — | — | WO | claimed |
| CN-109438318-B | Synthesis method of 3-aryl indole and derivatives thereof | 湖南医药学院 | 2022-05-03 | — | — | CN | claimed |
| CN-107619386-B | Aromatic ring [ c ] carbazole derivative and synthesis method thereof | 湘潭大学 | 2020-10-13 | — | — | CN | claimed |
| CN-106117113-B | Polysubstituted carbazole, derivative and its synthetic method | 湘潭大学 | 2019-08-16 | — | — | CN | claimed |
| CN-106995400-B | A kind of compound and its salt and its synthetic method | 湘潭大学 | 2019-08-06 | — | — | CN | claimed |
| CN-107235990-B | Polysubstituted indoles bithiophene and derivative and its synthetic method | 湘潭大学 | 2019-01-29 | — | — | CN | claimed |
| CN-108218897-A | Polysubstituted selenophen diindyl and derivative and its synthetic method | 湘潭大学 | 2018-06-29 | — | — | CN | claimed |
| CN-107619386-A | A kind of aromatic ring simultaneously [c] carbazole analog derivative and its synthetic method | 湘潭大学 | 2018-01-23 | — | — | CN | claimed |
| CN-107235990-A | Polysubstituted indoles bithiophene and derivative and its synthetic method | 湘潭大学 | 2017-10-10 | — | — | CN | claimed |
| CN-106995400-A | A kind of compound and its salt and its synthetic method | 湘潭大学 | 2017-08-01 | — | — | CN | claimed |
| CN-104788359-A | Synthesis method of copper-promoted 3-cyano-substituted-indole compound | UNIV HUNAN | 2015-07-22 | — | — | CN | claimed |
| US-12404261-B2 | Compounds and compositions for treating conditions associated with cGAS | NOVARTIS AG (CH) | 2025-09-02 | — | — | US | disclosed |
| US-20250263760-A1 | MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2025-08-21 | — | — | US | disclosed |
| US-4443615-A | ANILINE, GLYCOL OR EPOXIDE, SILICA AND/OR ALUMINA CATALYST | TANABE SEIYAKU CO., LTD. (JP) | 1984-04-17 | — | — | US | disclosed |
| EP-0072932-A2 | Piperazinones, their preparation and use | CASSELLA Aktiengesellschaft (DE) | 1983-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12404261-B2 | Compounds and compositions for treating conditions associated with cGAS | CGAS, TDP1, IAPP | PRKCI 1580/4885HTR2C 1303/4885L3MBTL1 2656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.