SCHEMBL723359

SCHEMBL723359

O=C1c2ccccc2CCN1C1CCNCC1

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 14/20 0.61
HTR2B P41595 11/20 0.61
HTR2A P28223 10/20 0.61
KDM5A P29375 1/20 0.47
PARP1 P09874 1/20 0.47
CRBN Q96SW2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30015409 1.00 HTR2C (0.61) HTR2CHTR2BHTR2AKDM5APARP1
Hydrochloric Acid SCHEMBL11737591 0.98 HTR2C (0.59) HTR2CHTR2BHTR2AKDM5APARP1
SCHEMBL30169487 0.91 HTR2C (0.70) HTR2CHTR2BHTR2APARP1
SCHEMBL21040315 0.89 HTR2C (0.56) HTR2CHTR2BHTR2AKDM5ACRBN
Hydrochloric Acid SCHEMBL30321070 0.87 HTR2C (0.55) HTR2CHTR2BHTR2AKDM5ACRBN
SCHEMBL28985479 0.86 HTR2C (0.54) HTR2CHTR2BHTR2AKDM5A
SCHEMBL7230144 0.84 HTR2C (0.52) HTR2CHTR2BHTR2A
SCHEMBL1976916 0.84 PARP1 (0.56) HTR2CHTR2BHTR2AKDM5APARP1
SCHEMBL16334116 0.83 HTR2B (0.67) HTR2CHTR2BHTR2APARP1
SCHEMBL16336941 0.83 HTR2B (0.67) HTR2CHTR2BHTR2APARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240174631-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FGF ACTIVITY RECOVERY THERAPEUTICS, INC. 2024-05-30 US disclosed
EP-4291177-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FGF ACTIVITY Recovery Therapeutics, Inc. (US) 2023-12-20 EP disclosed
CN-117157069-A Compounds, compositions and methods for modulating FGF activity 康复治疗公司 2023-12-01 CN disclosed
WO-2012025155-A1 HYDROXAMATE-BASED INHIBITORS OF DEACETYLASES NOVARTIS AG (CH) 2012-03-01 WO disclosed
US-20110053925-A1 Hydroxamate-Based Inhibitors of Deacetylases NOVARTIS AG 2011-03-03 US disclosed
US-4304912-A Piperidine derivatives CIBA-GEIGY CORPORATION (US) 1981-12-08 US disclosed
US-4029795-A 4(2' Isoquinolin-1-one)piperidines CIBA-GEIGY CORPORATION (US) 1977-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174631-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FGF ACTIVITY FGF1, FGF2, FGFR1 HTR2C 1517/4885HTR2B 2151/4885HTR2A 1239/4885
US-20110053925-A1 Hydroxamate-Based Inhibitors of Deacetylases HDAC1, HDAC11, HDAC3 HTR2C 2313/4885HTR2B 1760/4885HTR2A 2151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.