Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.65 |
| ▸ | ITK | Q08881 | 15/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7233461 | 0.99 | GRM1 (0.64) | GRM1ITKALDH1A1MAPTHPGD | |
| SCHEMBL7233634 | 0.93 | GRM1 (0.75) | GRM1ITKALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL7233449 | 0.93 | GRM1 (0.74) | GRM1ITKALDH1A1MAPTHPGD | |
| SCHEMBL658904 | 0.86 | GRM1 (0.87) | GRM1ITKALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL7232011 | 0.83 | GRM1 (0.62) | GRM1ITKALDH1A1MAPTHPGD | |
| SCHEMBL14453251 | 0.83 | GRM1 (0.53) | GRM1ITKALDH1A1MAPTHPGD | |
| SCHEMBL7241308 | 0.83 | GRM1 (0.44) | GRM1ITK | |
| Hydrochloric Acid SCHEMBL7233125 | 0.82 | GRM1 (0.61) | GRM1ITKALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL7241481 | 0.82 | GRM1 (0.43) | GRM1ITK | |
| SCHEMBL7240200 | 0.79 | GRM1 (0.67) | GRM1ITKALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642264-B1 | Thiazolo(3,2-a)benzoimidazole derivatives act specifically on metabotropic glutamate receptors and are used as medicaments. | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2003-11-04 | — | — | US | claimed |
| EP-1167369-A1 | NOVEL THIAZOLOBENZIMIDAZOLE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2002-01-02 | — | — | EP | claimed |
| US-6642264-B1 | Thiazolo(3,2-a)benzoimidazole derivatives act specifically on metabotropic glutamate receptors and are used as medicaments. | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| EP-1167369-A1 | NOVEL THIAZOLOBENZIMIDAZOLE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |