Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7238413 | 0.93 | BTK (0.35) | BTKEPHX1KDM1ACTSKNFKB1 | |
| SCHEMBL7231875 | 0.89 | BTK (0.40) | BTKEPHX1KDM1ACTSKNFKB1 | |
| SCHEMBL7238417 | 0.89 | BTK (0.40) | BTKEPHX1KDM1ACTSKNFKB1 | |
| SCHEMBL7231122 | 0.87 | BTK (0.40) | BTKEPHX1KDM1ACTSKNFKB1 | |
| SCHEMBL7239017 | 0.82 | BTK (0.44) | BTKEPHX1KDM1ACTSKNFKB1 | |
| SCHEMBL7896009 | 0.81 | NAAA (0.33) | EPHX1 | |
| SCHEMBL7230501 | 0.80 | EPHX1 (0.36) | BTKEPHX1 | |
| SCHEMBL7234217 | 0.79 | — | — | |
| SCHEMBL7235642 | 0.77 | BTK (0.38) | BTKEPHX1KDM1ACTSKNFKB1 | |
| SCHEMBL7231707 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518305-B1 | For inhibiting neuraminidases from disease- causing microorganisms, especially, influenza neuraminidase | ABBOTT LABORATORIES | 2003-02-11 | — | — | US | disclosed |