Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | FADS1 | O60427 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795345 | 0.85 | MAPT (0.61) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL1488257 | 0.81 | — | — | |
| SCHEMBL2481143 | 0.79 | MAPT (0.55) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8714373 | 0.77 | MAPT (0.53) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL20954869 | 0.77 | MAPT (0.53) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL1337290 | 0.77 | MAPT (0.53) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL10669562 | 0.77 | MAPT (0.58) | MAPTALDH1A1GAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1091453 | 0.76 | MAPT (0.52) | MAPTALDH1A1GAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11064752 | 0.76 | MAPT (0.56) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL1686631 | 0.75 | FADS1 (0.59) | MAPTALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552192-B1 | Inhibiting cyclin dependent kinase proteins, viruses, and immunostimulation; antimitotic, antiviral, anticancinogenic, antidegenerative, immunosuppressive | USTAU EXPERIMENTALNI BOTANIKY AV-CR (CZ) | 2003-04-22 | — | — | US | disclosed |