SCHEMBL7234945

SCHEMBL7234945

COC(=O)c1cc(C(=O)O)cc(C(=O)OC)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.60
CA1 P00915 4/20 0.60
CA2 P00918 4/20 0.60
CA7 P43166 4/20 0.60
CA9 Q16790 4/20 0.60
CA14 Q9ULX7 4/20 0.60
KDM4E B2RXH2 7/20 0.59
ALDH1A1 P00352 1/20 0.59
XDH P47989 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
LMNA P02545 2/20 0.58
POLB P06746 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
GAA P10253 1/20 0.58
NFKB1 P19838 1/20 0.58
GFER P55789 1/20 0.58
NFKB2 Q00653 1/20 0.58
RELA Q04206 1/20 0.58
FUT7 Q11130 1/20 0.58
TSHR P16473 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9121827 1.00 CA12 (0.60) CA12CA1CA2CA7CA9
Methyl Alcohol SCHEMBL28269742 0.98 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL6734277 0.91 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL17274803 0.91 CA12 (0.76) CA12CA1CA2CA7CA9
SCHEMBL31455886 0.91 CA12 (0.76) CA12CA1CA2CA7CA9
SCHEMBL14301421 0.91 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL1174380 0.91 CA12 (0.76) CA12CA1CA2CA7CA9
SCHEMBL166126 0.91 TPMT (0.64) CA12CA1CA2CA7CA9
SCHEMBL23699475 0.89 KDM4E (0.50) CA12CA1CA2CA7CA9
SCHEMBL8006121 0.89 KDM4E (0.50) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778153-B Amido bridged hexacarboxylic acid ligand and metal organic framework material as well as preparation method and application thereof 湖南科技大学 2023-03-14 CN claimed
CN-100363323-C Hydrogenation of benzene polycarboxylic acids or derivatives thereof EXXONMOBIL CHEM PATENTS INC (US) 2008-01-23 CN claimed
CN-1726179-A Hydrogenation of benzene polycarboxylic acids or derivatives thereof EXXONMOBIL CHEM PATENTS INC (US) 2006-01-25 CN claimed
EP-4687854-A2 LIPIDS AND LIPID-LIKE COMPOUNDS FOR THERAPEUTIC LIPID NANOPARTICLE (LNP) DELIVERY Flagship Labs 114, Inc. (US) 2026-02-11 EP disclosed
CN-118955391-A Substituted N- (2-oxo ethyl) benzamide derivative and preparation method and application thereof 中国医学科学院医药生物技术研究所 2024-11-15 CN disclosed
EP-4452930-A1 IONIZABLE AMINE AND ESTER LIPIDS AND LIPID NANOPARTICLES Beam Therapeutics Inc. (US) 2024-10-30 EP disclosed
WO-2024211865-A2 LIPIDS AND LIPID-LIKE COMPOUNDS FOR THERAPEUTIC LIPID NANOPARTICLE (LNP) DELIVERY OMEGA THERAPEUTICS, INC. (US) 2024-10-10 WO disclosed
US-20240335543-A1 IONIZABLE AMINE AND ESTER LIPIDS AND LIPID NANOPARTICLES BEAM THERAPEUTICS INC. 2024-10-10 US disclosed
WO-2023121970-A1 IONIZABLE AMINE AND ESTER LIPIDS AND LIPID NANOPARTICLES BEAM THERAPEUTICS INC. (US) 2023-06-29 WO disclosed
WO-2023121970-A1 IONIZABLE AMINE AND ESTER LIPIDS AND LIPID NANOPARTICLES BEAM THERAPEUTICS INC. (US) 2023-06-29 WO disclosed
CN-112778153-B Amido bridged hexacarboxylic acid ligand and metal organic framework material as well as preparation method and application thereof 湖南科技大学 2023-03-14 CN disclosed
CN-1285815-A Process for hydrogenating benzenepolycarboxylic acids or derivatives thereof using catalysts containing macropores BASF AG (DE) 2001-02-28 CN disclosed
EP-0642569-B1 POLYESTERS OF POLY(OXYALKYLENE) HYDROXYAROMATIC ETHERS CHEVRON CHEM CO (US) 1998-12-16 EP disclosed
CN-1197453-A 4-mercaptopyrrolidine derivatives as farnesyl transferase inhibitors ZENECA LTD (GB) 1998-10-28 CN disclosed
EP-0842151-A1 4-MERCAPTOPYRROLIDINE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS ZENECA LIMITED (GB) 1998-05-20 EP disclosed
WO-1996034851-A1 BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE ABBOTT LABORATORIES (US) 1996-11-07 WO disclosed
EP-0642569-A4 POLYESTERS OF POLY(OXYALKYLENE) HYDROXYAROMATIC ETHERS. CHEVRON CHEM CO (US) 1995-08-09 EP disclosed
EP-0642569-A1 POLYESTERS OF POLY(OXYALKYLENE) HYDROXYAROMATIC ETHERS CHEVRON CHEMICAL COMPANY (US) 1995-03-15 EP disclosed
WO-1994020592-A1 POLYESTERS OF POLY(OXYALKYLENE) HYDROXYAROMATIC ETHERS CHEVRON RESEARCH AND TECHNOLOGY COMPANY A DIVISION OF CHEVRON U.S.A. INC. (US) 1994-09-15 WO disclosed
US-5296003-A Fuel additives CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1994-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240335543-A1 IONIZABLE AMINE AND ESTER LIPIDS AND LIPID NANOPARTICLES PHOSPHO1, SGMS1, SGMS2 CA12 711/4885CA1 1198/4885CA2 1769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.