Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.60 |
| ▸ | PDE2A | O00408 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | XDH | P47989 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29310490 | 0.83 | GSK3B (0.79) | GSK3BPDE2AHPGDXDHPOLB | |
| SCHEMBL4822785 | 0.83 | GSK3B (0.84) | GSK3BHPGDXDHPOLBSMN1; SMN2 | |
| SCHEMBL7228356 | 0.82 | GSK3B (0.69) | GSK3BPDE2AHPGDXDH | |
| SCHEMBL28132422 | 0.77 | GSK3B (0.70) | GSK3BHPGDXDHPOLBSMN1; SMN2 | |
| SCHEMBL5381549 | 0.76 | GSK3B (1.00) | GSK3BHPGDXDHPOLBSMN1; SMN2 | |
| SCHEMBL23054678 | 0.74 | GSK3B (0.65) | GSK3BPDE2AHPGDXDHPOLB | |
| SCHEMBL28133262 | 0.74 | GSK3B (0.65) | GSK3BPDE2AHPGDXDHHTT | |
| SCHEMBL801944 | 0.73 | GSK3B (0.56) | GSK3BHPGDXDHPOLBSMN1; SMN2 | |
| SCHEMBL16867726 | 0.73 | PDE2A (1.00) | PDE2A | |
| SCHEMBL5384455 | 0.72 | GSK3B (0.75) | GSK3BHPGDXDHPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620817-B1 | Antiinflammatory, antiarthritic agents; autoimmune and rheumatic diseases | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2003-09-16 | — | — | US | disclosed |