Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | CDC7 | O00311 | 1/20 | 0.59 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.54 |
| ▸ | XDH | P47989 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14935666 | 0.98 | GSK3B (0.73) | GSK3BKMT2ACDC7DBF4CYP19A1 | |
| SCHEMBL5381426 | 0.92 | GSK3B (0.78) | GSK3BKMT2ACDC7DBF4CYP19A1 | |
| SCHEMBL5376063 | 0.88 | GSK3B (0.76) | GSK3BKMT2ACDC7DBF4CYP19A1 | |
| SCHEMBL4822785 | 0.87 | GSK3B (0.84) | GSK3BKMT2ACDC7DBF4MAPT | |
| SCHEMBL5381549 | 0.86 | GSK3B (1.00) | GSK3BCDC7DBF4MAPTGAA | |
| SCHEMBL2239607 | 0.85 | CYP2A6 (0.59) | GSK3BKMT2ACDC7DBF4CYP19A1 | |
| SCHEMBL29310490 | 0.83 | GSK3B (0.79) | GSK3BKMT2ACDC7DBF4MAPT | |
| SCHEMBL5385544 | 0.80 | GSK3B (0.64) | GSK3BKMT2ACDC7DBF4MAPT | |
| SCHEMBL5400045 | 0.79 | GSK3B (0.69) | GSK3BKMT2ACYP19A1HPGDXDH | |
| SCHEMBL14935661 | 0.79 | GSK3B (0.55) | GSK3BKMT2ACDC7DBF4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| EP-1115721-B1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2003-12-10 | — | — | EP | disclosed |
| EP-1115721-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018758-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-04-06 | — | — | WO | disclosed |