SCHEMBL723544

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL723261	0.83	PDE4C (0.43)	PDE4CJAK2JAK1GAKRIPK2
	SCHEMBL723093	0.77	PDE4C (0.55)	PDE4CJAK2JAK1SYKPTGES
	SCHEMBL723294	0.77	PDE4C (0.47)	PDE4CJAK2JAK1GAKRIPK2
	SCHEMBL723027	0.76	PTGES (0.47)	PDE4CJAK2JAK1GAKRIPK2
	SCHEMBL722839	0.75	PDE4C (0.51)	PDE4CJAK2JAK1TUBB4ATUBB
	SCHEMBL724141	0.75	PDE4C (0.48)	PDE4CJAK2JAK1SYKPTGES
	SCHEMBL722312	0.75	JAK2 (0.48)	PDE4CJAK2JAK1TUBB4ATUBB
	SCHEMBL723585	0.75	PDE4C (0.51)	PDE4CJAK2JAK1GAKRIPK2
	SCHEMBL724908	0.74	PDE4C (0.53)	PDE4CJAK2JAK1SYKPTGES
	SCHEMBL723790	0.74	PDE4C (0.47)	PDE4CJAK2JAK1SYKPTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.