Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | MTTP | P55157 | 2/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7236097 | 0.93 | HTR7 (0.47) | HTR7HTR1ACHRM1CHRM2CHRM4 | |
| SCHEMBL7238366 | 0.92 | KCNA3 (0.42) | HTR7HTR1ACHRM1KCNA3CHRM2 | |
| SCHEMBL7241813 | 0.92 | HTR7 (0.46) | HTR7HTR1ACHRM1CHRM2CHRM4 | |
| SCHEMBL7244298 | 0.92 | KCNA3 (0.43) | HTR7HTR1ACHRM1KCNA3CHRM2 | |
| SCHEMBL7241472 | 0.91 | HTR7 (0.46) | HTR7HTR1ACHRM1KCNA3CHRM2 | |
| SCHEMBL7231946 | 0.91 | HTR7 (0.48) | HTR7HTR1ACHRM1KCNA3CHRM2 | |
| SCHEMBL7235521 | 0.91 | HTR7 (0.45) | HTR7HTR1ACHRM1CHRM2CHRM4 | |
| SCHEMBL7244723 | 0.91 | HTR7 (0.47) | HTR7HTR1ACHRM1CHRM2CHRM4 | |
| SCHEMBL7237774 | 0.90 | KCNA3 (0.42) | HTR7HTR1ACHRM1KCNA3CHRM2 | |
| SCHEMBL7236422 | 0.88 | KCNA3 (0.44) | HTR7CHRM1KCNA3CHRM2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617325-B1 | Inhibitors of the microsomal triglyceride-transfer protein | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-09-09 | — | — | US | disclosed |