Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.63 |
| ▸ | CTSK | P43235 | 4/20 | 0.63 |
| ▸ | CTSL | P07711 | 2/20 | 0.59 |
| ▸ | CTSB | P07858 | 2/20 | 0.59 |
| ▸ | PPARA | Q07869 | 2/20 | 0.58 |
| ▸ | ACE | P12821 | 1/20 | 0.57 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1486267 | 1.00 | CTSS (0.63) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL16163459 | 1.00 | CTSS (0.63) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL85543 | 0.95 | CTSS (0.64) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL22404737 | 0.95 | CTSS (0.64) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL3355326 | 0.95 | CTSS (0.64) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL7409385 | 0.93 | CTSS (0.65) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL7409389 | 0.93 | CTSS (0.65) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL23729806 | 0.92 | CTSS (0.58) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL24942151 | 0.92 | CTSS (0.58) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL16355883 | 0.92 | CTSS (0.58) | CTSSCTSKCTSLCTSBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602876-B1 | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2003-08-05 | — | — | US | disclosed |
| US-6204280-B1 | OXAZOLIDINONE DERIVATIVE, ANTICOAGULANT | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKTER HAFTUNG (DE) | 2001-03-20 | — | — | US | disclosed |
| CN-1057760-C | Amino acid-substituted benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent and a medicament containing them | HOECHST AG (DE) | 2000-10-25 | — | — | CN | disclosed |
| EP-0710657-B1 | Antagonists of adhesion receptors | MERCK PATENT GMBH (DE) | 1998-08-26 | — | — | EP | disclosed |
| US-5631293-A | CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-20 | — | — | US | disclosed |
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |
| CN-1127749-A | Amino acid-substituted benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent and a medicament containing them | HOECHST AG (DE) | 1996-07-31 | — | — | CN | disclosed |
| EP-0710657-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-08 | — | — | EP | disclosed |