Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 19/20 | 0.82 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573985 | 0.91 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL7237629 | 0.91 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL1573941 | 0.89 | CCR5 (0.82) | CCR5KCNH2 | |
| SCHEMBL7244431 | 0.86 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL7244425 | 0.86 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL7244674 | 0.86 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL7241883 | 0.83 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL7239042 | 0.83 | CCR5 (0.87) | CCR5KCNH2 | |
| SCHEMBL7244123 | 0.83 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL1574000 | 0.83 | CCR5 (0.81) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586430-B1 | Administering azabicyclo compounds to treat human immunodeficiency virus infections and respiratory system disorders | PFIZER INC. | 2003-07-01 | — | — | US | disclosed |