Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235806 | 0.95 | MAPK1 (0.48) | MAPK1L3MBTL1ITGB3ITGA2BGRM2 | |
| SCHEMBL7228301 | 0.95 | MAPK1 (0.48) | MAPK1L3MBTL1ITGB3ITGA2BGRM2 | |
| SCHEMBL7238185 | 0.90 | MAPK1 (0.43) | MAPK1L3MBTL1ITGB3ITGA2BGRM2 | |
| SCHEMBL7238538 | 0.87 | MAPK1 (0.45) | MAPK1L3MBTL1ITGB3ITGA2BGRM2 | |
| SCHEMBL7229609 | 0.86 | ITGB3 (0.44) | MAPK1L3MBTL1ITGB3ITGA2BGRM2 | |
| SCHEMBL7235888 | 0.85 | MAPK1 (0.49) | MAPK1L3MBTL1ITGB3ITGA2BGRM2 | |
| SCHEMBL7229583 | 0.85 | MAPK1 (0.46) | MAPK1L3MBTL1ITGB3ITGA2BGRM2 | |
| SCHEMBL7235258 | 0.85 | MAPK1 (0.46) | MAPK1L3MBTL1ITGB3ITGA2BGRM2 | |
| SCHEMBL7236119 | 0.85 | ITGB3 (0.47) | MAPK1L3MBTL1ITGB3ITGA2B | |
| SCHEMBL7239563 | 0.84 | ITGB3 (0.42) | MAPK1L3MBTL1ITGB3ITGA2BGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602876-B1 | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2003-08-05 | — | — | US | disclosed |
| US-6204280-B1 | OXAZOLIDINONE DERIVATIVE, ANTICOAGULANT | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKTER HAFTUNG (DE) | 2001-03-20 | — | — | US | disclosed |
| EP-0710657-B1 | Antagonists of adhesion receptors | MERCK PATENT GMBH (DE) | 1998-08-26 | — | — | EP | disclosed |
| EP-0710657-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-08 | — | — | EP | disclosed |