Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | BRAF | P15056 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31180472 | 0.86 | KAT6A (0.58) | ALDH1A1KDM4EKMT2AGPR139KAT6A | |
| SCHEMBL679553 | 0.86 | KAT6A (0.58) | ALDH1A1KDM4EKMT2AGPR139KAT6A | |
| Hydrochloric Acid SCHEMBL30978290 | 0.85 | KAT6A (0.56) | ALDH1A1KDM4EKMT2AGPR139KAT6A | |
| SCHEMBL6580853 | 0.84 | KMT2A (0.61) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL20166696 | 0.83 | KMT2A (0.59) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL4492988 | 0.83 | RAB9A (0.63) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL10664357 | 0.81 | TRPV1 (0.61) | MAPTHTTALDH1A1KDM4EKMT2A | |
| SCHEMBL978712 | 0.81 | AKR1C3 (0.54) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL4035515 | 0.81 | MAPT (0.56) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL5866992 | 0.80 | MAPT (0.49) | MAPTRAB9ANPC1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |