SCHEMBL7239013

SCHEMBL7239013

CCCCCC=C(F)c1ccc(-c2ccc(CC)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RARB P10826 7/20 0.43
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
RARA P10276 1/20 0.42
MAPT P10636 1/20 0.42
MTOR P42345 1/20 0.42
HRH4 Q9H3N8 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
BDKRB2 P30411 2/20 0.36
THRA P10827 4/20 0.36
THRB P10828 4/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7239009 1.00 RARB (0.43) RARBALDH1A1MEN1KMT2ARARA
SCHEMBL7228506 0.89 RARB (0.49) RARBALDH1A1MEN1KMT2ARARA
SCHEMBL7228510 0.89 RARB (0.49) RARBALDH1A1MEN1KMT2ARARA
SCHEMBL7229653 0.88 RARB (0.57) RARBALDH1A1MEN1KMT2ARARA
SCHEMBL7229660 0.88 RARB (0.57) RARBALDH1A1MEN1KMT2ARARA
SCHEMBL7231010 0.84 RARB (0.47) RARBALDH1A1MEN1KMT2ARARA
SCHEMBL7765141 0.84 RARB (0.47) RARBALDH1A1MEN1KMT2ARARA
SCHEMBL7231017 0.84 RARB (0.47) RARBALDH1A1MEN1KMT2ARARA
SCHEMBL7231049 0.84 RARB (0.47) RARBALDH1A1MEN1KMT2ARARA
SCHEMBL7230003 0.82 ACACB (0.37) RARBALDH1A1RARASMN1; SMN2THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6623810-B2 Refractive index anisotropy SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-09-23 US disclosed
US-20010050353-A1 Phenylacetylene compound, liquid crystal composition, and liquid crystal element produced with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-13 US disclosed
EP-0781827-B1 Liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL CO (JP) 2001-06-13 EP disclosed
US-5866035-A LARGE BIREFRINGENCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-02 US disclosed
EP-0781827-A1 Liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-02 EP disclosed