SCHEMBL7765141

SCHEMBL7765141

CCCCC=C(F)c1ccc(-c2ccc(-c3ccc(CCC)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RARB P10826 7/20 0.47
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.45
RARA P10276 1/20 0.45
MTOR P42345 1/20 0.45
THRB P10828 6/20 0.41
THRA P10827 5/20 0.40
PLK1 P53350 2/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
PLA2G1B P04054 1/20 0.37
ATG4B Q9Y4P1 1/20 0.37
MCL1 Q07820 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7231010 1.00 RARB (0.47) RARBKMT2AMEN1ALDH1A1MAPT
SCHEMBL7231049 1.00 RARB (0.47) RARBKMT2AMEN1ALDH1A1MAPT
SCHEMBL7231017 1.00 RARB (0.47) RARBKMT2AMEN1ALDH1A1MAPT
SCHEMBL7228510 0.95 RARB (0.49) RARBKMT2AMEN1ALDH1A1MAPT
SCHEMBL7228506 0.95 RARB (0.49) RARBKMT2AMEN1ALDH1A1MAPT
SCHEMBL7229653 0.88 RARB (0.57) RARBKMT2AMEN1ALDH1A1MAPT
SCHEMBL7229660 0.88 RARB (0.57) RARBKMT2AMEN1ALDH1A1MAPT
SCHEMBL7239013 0.84 RARB (0.43) RARBKMT2AMEN1ALDH1A1MAPT
SCHEMBL7239009 0.84 RARB (0.43) RARBKMT2AMEN1ALDH1A1MAPT
SCHEMBL7231979 0.84 RARB (0.51) RARBKMT2AMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0781827-B1 Liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL CO (JP) 2001-06-13 EP disclosed
US-6149837-A SUBSTITUTED 1,4-BIS(SUBSTITUED PHENYLACETYLENE)BENZENE WHERE AT LEAST ONE RING HAS AN ALKYL ATTACHMENT, HAS A LARGE ANISOTROPY OF REFRACTIVE INDEX, TENDS TO BE MIXED WITH OTHER LIQUID CRYSTALS, IS LIGHT STABLE; LIQUID CRYSTAL ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-11-21 US disclosed
US-5866035-A LARGE BIREFRINGENCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-02 US disclosed
EP-0781827-A1 Liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-02 EP disclosed