SCHEMBL7239177

SCHEMBL7239177

C=CCC(N)C(N)CC=C

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
GRIK1 P39086 2/20 0.37
GRIK2 Q13002 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8647042 1.00 ALDH1A1 (0.38) ALDH1A1GRIK1GRIK2
Hydrochloric Acid SCHEMBL7237514 0.96 GRIK1 (0.36) ALDH1A1GRIK1GRIK2
SCHEMBL23169097 0.86 GRIK1 (0.39) ALDH1A1GRIK1GRIK2
SCHEMBL28850175 0.83 GRIK1 (0.30) GRIK1GRIK2
SCHEMBL11144018 0.81
SCHEMBL175674 0.81
SCHEMBL28793360 0.81 GRIK1 (0.37) ALDH1A1GRIK1GRIK2
SCHEMBL9252395 0.80
SCHEMBL10630249 0.78
Hydrochloric Acid SCHEMBL6531375 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3053165-A None JP disclosed
JP-3010159-A None JP disclosed
CN-101687961-B Crosslinked polyallylamine or acid addition salt thereof, and use thereof for medical purposes TORAY INDUSTRIES 2011-10-05 CN disclosed
CN-101687961-A Crosslinked polyallylamine or acid addition salt thereof, and use thereof for medical purposes TORAY INDUSTRIES 2010-03-31 CN disclosed
US-6525041-B1 Low molecular weight mimics of superoxide dismutase; inflammatory disorders, ischemic/reperfusion injury, stroke, atherosclerosis, and all other conditions of oxidant- induced tissue damage or injury PHARMACIA CORPORATION 2003-02-25 US disclosed
US-5976498-A Methods of diagnostic image analysis using metal complexes of nitrogen-containing macrocyclic ligands MONSANTO COMPANY 1999-11-02 US disclosed
US-5969015-A FOR ENHANCING PERFORMANCE PROPERTIES OF LUBRICANTS, HYDRAULIC FLUIDS OR METAL PROCESSING FLUIDS WITCO VINYL ADDITIVES GMBH (DE) 1999-10-19 US disclosed
CN-1191530-A Manganese or iron complexes of nitrogen-contg. macrocyclic ligands effective as catalysts for dismutating superoxide MONSANTO CO (US) 1998-08-26 CN disclosed
EP-0844889-A1 METHODS OF DIAGNOSTIC IMAGE ANALYSIS USING METAL COMPLEXES OF NITROGEN-CONTAINING MACROCYCLIC LIGANDS MONSANTO COMPANY (US) 1998-06-03 EP disclosed
EP-0830352-A1 MANGANESE OR IRON COMPLEXES OF NITROGEN-CONTAINING MACROCYCLIC LIGANDS EFFECTIVE AS CATALYSTS FOR DISMUTATING SUPEROXIDE MONSANTO COMPANY (US) 1998-03-25 EP disclosed
WO-1997006831-A1 METHODS OF DIAGNOSTIC IMAGE ANALYSIS USING METAL COMPLEXES OF NITROGEN-CONTAINING MACROCYCLIC LIGANDS MONSANTO COMPANY (US) 1997-02-27 WO disclosed
WO-1996039396-A1 MANGANESE OR IRON COMPLEXES OF NITROGEN-CONTAINING MACROCYCLIC LIGANDS EFFECTIVE AS CATALYSTS FOR DISMUTATING SUPEROXIDE MONSANTO COMPANY (US) 1996-12-12 WO disclosed
EP-0641309-A1 SYNTHESIS OF VICINAL DIAMINES MALLINCKRODT MEDICAL, INC. (US) 1995-03-08 EP disclosed
WO-1993003003-A1 SYNTHESIS OF VICINAL DIAMINES MALLINCKRODT MEDICAL, INC. (US) 1993-02-18 WO disclosed
US-5105014-A Synthesis of vicinal diamines MALLINCKRODT MEDICAL, INC. (US) 1992-04-14 US disclosed
JP-H0353165-A FLUORESCENCE DETECTION USING PEROXIDASE AS LABELING ENZYME YUKI GOSEI KOGYO CO LTD 1991-03-07 JP disclosed
JP-H0310159-A METHOD FOR DETERMINING QUANTITY OF RIBONUCLEIC ACID YUKI GOSEI KOGYO CO LTD 1991-01-17 JP disclosed