SCHEMBL723918

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL722839	0.85	PDE4C (0.51)	PDE4CJAK2JAK1TYK2CYP1A1
	SCHEMBL721530	0.85	PDE4C (0.47)	PDE4CJAK2JAK1TYK2FYN
	SCHEMBL722497	0.84	PDE4C (0.47)	PDE4CJAK2JAK1TYK2CYP1A1
	SCHEMBL723597	0.83	FYN (0.54)	PDE4CJAK2JAK1TYK2ALDH1A1
	SCHEMBL722112	0.82	RPS6KA2 (0.48)	PDE4CCYP1A1CYP1A2KDM4EALDH1A1
	SCHEMBL723760	0.81	PDE4C (0.43)	PDE4CJAK2JAK1TYK2KDM4E
	SCHEMBL16638609	0.81	PDE4C (0.50)	PDE4CJAK2JAK1TYK2CYP1A1
	SCHEMBL723093	0.81	PDE4C (0.55)	PDE4CJAK2JAK1TYK2CYP1A1
	SCHEMBL10267650	0.81	FYN (0.54)	PDE4CJAK2JAK1TYK2ALDH1A1
	SCHEMBL722312	0.80	JAK2 (0.48)	PDE4CJAK2JAK1TYK2CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.