Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 15/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355215 | 0.84 | TLR7 (0.57) | TLR7TLR8NUDT1 | |
| SCHEMBL3353822 | 0.80 | AVPR1A (0.43) | TLR7TLR8NUDT1AVPR1APDE4A | |
| SCHEMBL6723860 | 0.75 | TLR7 (0.76) | TLR7TLR8NUDT1 | |
| SCHEMBL7231973 | 0.73 | AVPR1A (0.40) | TLR7TLR8NUDT1AVPR1APDE4A | |
| SCHEMBL6724451 | 0.71 | TLR7 (0.48) | TLR7TLR8NUDT1PDE4APDE4B | |
| SCHEMBL4377041 | 0.70 | TLR7 (0.52) | TLR7TLR8 | |
| SCHEMBL20447851 | 0.69 | TLR7 (0.72) | TLR7TLR8NUDT1 | |
| SCHEMBL13663018 | 0.69 | TLR7 (0.49) | TLR7TLR8NUDT1 | |
| SCHEMBL4155960 | 0.68 | TLR7 (0.62) | TLR7TLR8NUDT1 | |
| SCHEMBL2749012 | 0.68 | TLR8 (0.55) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624172-B2 | Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor, and useful as viricides and antitumor agents | 3M INNOVATIVE PROPERTIES COMPANY | 2003-09-23 | — | — | US | claimed |