Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4160150 | 0.83 | TLR7 (0.49) | TLR7TLR8MEN1KMT2ATSHR | |
| SCHEMBL5617306 | 0.81 | TLR8 (0.35) | TLR7TLR8MEN1KMT2ATP53 | |
| SCHEMBL3353822 | 0.80 | AVPR1A (0.43) | AVPR1ATLR7TLR8MEN1KMT2A | |
| SCHEMBL2749843 | 0.80 | MEN1 (0.36) | TLR7TLR8MEN1KMT2ATSHR | |
| SCHEMBL4313942 | 0.79 | HTR5A (0.33) | TLR8 | |
| SCHEMBL1457245 | 0.78 | NPC1 (0.36) | MAPTPOLB | |
| SCHEMBL4155874 | 0.75 | MAOA (0.34) | TLR7TLR8MEN1KMT2ATSHR | |
| SCHEMBL3355215 | 0.74 | TLR7 (0.57) | TLR7TLR8NUDT1 | |
| SCHEMBL7231032 | 0.74 | TLR7 (0.42) | TLR7TLR8MEN1KMT2ATP53 | |
| SCHEMBL7239269 | 0.73 | TLR7 (0.44) | AVPR1ATLR7TLR8NUDT1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624172-B2 | Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor, and useful as viricides and antitumor agents | 3M INNOVATIVE PROPERTIES COMPANY | 2003-09-23 | — | — | US | disclosed |