⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14125002 | 0.67 | NOTUM (0.56) | — | |
| SCHEMBL12427497 | 0.65 | — | — | |
| SCHEMBL11149894 | 0.65 | — | — | |
| SCHEMBL9189318 | 0.64 | NOTUM (1.00) | — | |
| SCHEMBL6230488 | 0.63 | — | — | |
| SCHEMBL2009212 | 0.62 | — | — | |
| SCHEMBL573723 | 0.62 | — | — | |
| SCHEMBL7238701 | 0.62 | — | — | |
| SCHEMBL11735548 | 0.62 | — | — | |
| SCHEMBL11149882 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930720-A | Application of spinosyn derivative as pesticide | 利民化学有限责任公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-115785180-B | Spinosyn derivative as pesticide, and preparation method and application thereof | 利民化学有限责任公司 | 2025-03-07 | — | — | CN | disclosed |
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | SIGNALRX PHARMACEUTICALS, INC. (US) | 2023-09-19 | — | — | US | disclosed |
| WO-2018140730-A1 | THIENOPYRANONES AND FURANOPYRANONES AS KINASE, BROMODOMAIN, AND CHECKPOINT INHIBITORS | SIGNALRX PHARMACEUTICALS, INC. (US) | 2018-08-02 | — | — | WO | disclosed |
| US-6544982-B1 | 3-aryl-5-aminoisoxazole derivatives | MERCK & CO., INC. | 2003-04-08 | — | — | US | disclosed |
| CN-1402710-A | Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis | AGOURON PHARMA (US) | 2003-03-12 | — | — | CN | disclosed |