Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 19/20 | 0.57 |
| ▸ | FEN1 | P39748 | 19/20 | 0.57 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763724 | 0.85 | ALOX5AP (0.62) | ALOX5APFEN1 | |
| SCHEMBL9122272 | 0.84 | ALOX5AP (0.65) | ALOX5APFEN1 | |
| SCHEMBL7237315 | 0.82 | ALOX5AP (0.53) | ALOX5APFEN1PTGES2 | |
| SCHEMBL6628076 | 0.79 | ALOX5AP (0.59) | ALOX5APFEN1 | |
| SCHEMBL7130070 | 0.77 | ALOX5AP (0.55) | ALOX5APFEN1 | |
| SCHEMBL1795111 | 0.77 | ALOX5AP (0.62) | ALOX5APFEN1 | |
| SCHEMBL1968159 | 0.77 | ALOX5AP (0.59) | ALOX5APFEN1 | |
| SCHEMBL7128878 | 0.76 | ALOX5AP (0.53) | ALOX5APFEN1 | |
| SCHEMBL3831543 | 0.75 | ALOX5AP (0.60) | ALOX5APFEN1 | |
| SCHEMBL5885311 | 0.75 | ALOX5AP (0.58) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6548512-B1 | Pyrazole derivatives such as 1-(3-amidinophenyl)-3-methyl-2-((5-(2'-aminosulfonylphenyl-1-yl)pyrimidin-2 -yl)aminocarbonyl)pyrazole; treating thromboembolic disorders | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-04-15 | — | — | US | disclosed |
| US-6020357-A | CARDIOVASCULAR DISORDERS; ANTCOAGULANTS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-02-01 | — | — | US | disclosed |