Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL348037 | 0.79 | — | — | |
| SCHEMBL348036 | 0.79 | — | — | |
| SCHEMBL20771269 | 0.76 | TDP1 (0.36) | TDP1FFAR3 | |
| SCHEMBL7231561 | 0.76 | TDP1 (0.36) | TDP1FFAR3 | |
| SCHEMBL93369 | 0.69 | — | — | |
| SCHEMBL6522626 | 0.69 | TDP1 (0.50) | TDP1FFAR3 | |
| SCHEMBL6522609 | 0.69 | TDP1 (0.50) | TDP1FFAR3 | |
| SCHEMBL891538 | 0.69 | HAO1 (0.54) | TDP1FFAR3 | |
| SCHEMBL24358 | 0.68 | — | — | |
| SCHEMBL7789733 | 0.67 | HAO1 (0.52) | TDP1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6548512-B1 | Pyrazole derivatives such as 1-(3-amidinophenyl)-3-methyl-2-((5-(2'-aminosulfonylphenyl-1-yl)pyrimidin-2 -yl)aminocarbonyl)pyrazole; treating thromboembolic disorders | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-04-15 | — | — | US | disclosed |
| US-6020357-A | CARDIOVASCULAR DISORDERS; ANTCOAGULANTS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0946508-A1 | NITROGEN CONTAINING HETEROAROMATICS AS FACTOR Xa INHIBITORS | Du Pont Pharmaceuticals Company (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028269-A1 | NITROGEN CONTAINING HETEROAROMATICS AS FACTOR Xa INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |